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Leukocyte DNAmTL estimator

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Research algorithm, not a direct telomere-length assay or clinical diagnostic. Cohort associations with mortality and cardiovascular outcomes are predictive-validation evidence and do not establish clinical utility. Sources verified 2026-09-28: https://www.aging-us.com/article/102173/text

Kind
Research telomere-related algorithm
Type of test
DNA-methylation estimator of leukocyte telomere length
Sample
Leukocyte DNA methylation profiled on an Illumina array
Details
A 140-CpG estimator trained by regressing measured leukocyte telomere length on blood DNA-methylation data. Cell-culture results indicate that it partly reflects cell replication rather than telomere length itself.
Publications
Lu et al., Aging (2019), DOI 10.18632/aging.102173