2060.Life
community of scientists, VCs, MDs, & entrepreneurs who believe in radical life extension w/ mission to defeat Aging by 2060, by R&D, advocacy, hubs, & growing ecosystem
community of scientists, VCs, MDs, & entrepreneurs who believe in radical life extension w/ mission to defeat Aging by 2060, by R&D, advocacy, hubs, & growing ecosystem
Solve aging, preserve Africa’s biodiversity, make aging a treatable disease for a healthy lifespan
Concise, structured info on the field as sortable/filterable tables: Books, blogs, companies, conferences, databases, diagnostics, journals, nonprofits, objections, podcasts, videos, etc.
Canine health research, including a dedicated program on the biology of aging, older-dog health, cognitive dysfunction, and diseases and conditions associated with aging.
Accelerates the pace of scientific discoveries in aging by working to increase funding/focus for aging at NIH/FDA & with other efforts.
The field's first 501c4, for social and political action to combat age-related chronic conditions.
Drug discovery, biomarkers, and prevention programs for Alzheimer's disease grounded in the biology of aging
"Funding ambitious research in longevity and neuroscience"
Dedicated to aging research
Advance Healthy Aging through Biomedical Research with grants & fellowships, plus other initiatives.
Systemic amyloidosis, including protein misfolding, amyloid formation and deposition, proteostasis, biomarkers, organ damage, and therapeutic development.
Niemann-Pick disease type C, a lysosomal cholesterol-trafficking and storage disorder with progressive neurodegeneration.
Fundamental and translational autophagy research and its intersections with inflammation, metabolism, cell and tissue homeostasis, and disease.
Barth syndrome, an inherited mitochondrial disorder involving cardiolipin remodeling, cardiomyopathy, skeletal-muscle weakness, neutropenia, growth delay, and metabolic dysfunction.
Batten disease and neuronal ceroid lipofuscinoses, inherited lysosomal storage disorders characterized by intracellular lipopigment accumulation and progressive neurodegeneration.
Directly does stem cell & gene-editing experiments towards delaying aging & rejuvenating vital organs, ultimately radically extending human lifespan.
Develop UK longevity industry, academia, & policy, and help scale global longevity industry.
Bloom syndrome, a BLM helicase and DNA-repair disorder marked by genomic instability, growth restriction, immune problems, and elevated cancer risk.
Research on Alzheimer's disease and related dementias, age-related macular degeneration, and glaucoma, spanning disease mechanisms, diagnostics, prevention, and treatments.
Promoting & funding research into the causes & effects of the aging process.
First independent biomedical research institute focused solely on aging. Mission is to end the threat of age-related disease for this and future generations.
Regenerative medicine, stem-cell research, and cell and gene therapy development for diseases with unmet medical needs.
Molecular and cellular mechanisms of aging and aging-associated metabolic, cardiovascular, renal, cancer, neurodegenerative, and other diseases.
Cellular and environmental stress responses, molecular chaperones, heat-shock proteins, protein folding, and proteostasis in health and disease.
Making epigenetic aging clocks more accessible for use with preclinical & clinical studies, including clocks that predict future healthspan/lifespan & clocks for diverse mammalian species.
Autophagy research, including autophagy mechanisms, physiology, aging, neurodegeneration, infection, immunity, metabolism, and disease.
Education, resources, community, public policy advoacy towards curing aging / unlimited lifespans.
Alzheimer's disease mechanisms and interventions, including age-related proteostasis decline, amyloid and tau biology, protein clearance, inflammation, genetics, and resilience.
Leigh syndrome and mitochondrial disease research, with an initial emphasis on SURF1-related Leigh syndrome.
Disease-modifying Parkinson's research, including cellular waste disposal, protein aggregation, oxidative stress, mitochondrial function, and regenerative approaches.
Research and therapeutic development for Sanfilippo syndrome, a lysosomal storage disorder also known as mucopolysaccharidosis type III.
VCP-associated multisystem proteinopathy affecting muscle, bone, brain, and peripheral nerves, with relevance to protein degradation, autophagy, endoplasmic-reticulum quality control, lysosomal function, and mitochondrial homeostasis.
Progressive supranuclear palsy, corticobasal degeneration, and multiple system atrophy research, including tau biology, autophagy, proteostasis, lysosomal biology, epigenetics, biomarkers, and regenerative approaches.
Study tens of thousands of companion dogs for 10 years for maximizing healthy longevity.
Fundamental mechanisms of cellular and tissue aging, including protein aggregation and proteostasis, stem-cell aging, senescence, DNA replication and repair, genome stability, gene regulation, and metabolism.
Feline health research, including mitochondrial and antioxidant biomarkers of aging, cognitive dysfunction, geriatric care, and age-related disease.
Fanconi anemia, cancers driven by defects in the FA/BRCA DNA-repair pathway, bone-marrow failure, and systemic inflammatory and aging manifestations.
Efforts to vastly extend healthy lifespan via several initiatives including reseacrh funding, supporting startups, events, research summaries.
Friedreich's ataxia, a frataxin-deficiency disorder involving mitochondrial iron-sulfur-cluster biology, oxidative stress, neurodegeneration, cardiomyopathy, skeletal-muscle impairment, and diabetes.
Interdisciplinary aging research, education, clinical practice, policy, and dissemination
extend healthy years via research on mechanisms of normal human aging & physiological decline, to translate research into interventions that will extend healthspan with lifespan
Public policy think tank for R&D towards treatments for underlying causes of aging-related disease. Education, policy research, lobbying, & coalition development.
Welfare, medical access, adoption, shelter diversion, and long-term home retention for senior dogs, with national data collection on older-dog needs and outcomes.
Stem-cell biology and regenerative medicine, including how aging and fibrosis affect disease, tissue repair, and therapeutic development.
TBD....
Public policy coalition on healthspan.
Grants & early sage investment to grow the number of researchers, companies, & amount of funding in the aging/longevity field.
Huntington's disease mechanisms and therapeutics, including somatic CAG-repeat instability, protein aggregation, neuronal vulnerability, gene regulation, and related neurodegeneration.
Systems biology and translational biomedical research, including multimodal studies of human longevity and age-related disease
Molecular mechanisms of aging, development, and disease, with emphasis on gene regulation, epigenetics, DNA repair, genome stability, telomere biology, and proteostasis.
Werner syndrome and atypical segmental progeroid syndromes involving WRN helicase, genome maintenance, premature age-related disease, cancer, atherosclerosis, diabetes, osteoporosis, and cataracts.
Biology of aging at molecular, cellular, organismal, and systems levels, with emphasis on root causes and prevention of age-associated disease.
Aging research news, crowdfunding, and advocacy. Social media outreach, community building, & education.
Loeys-Dietz syndrome and related genetic aortic and connective-tissue disease involving TGF-beta signaling, extracellular-matrix integrity, arterial aneurysm, and multisystem manifestations.
Open discussion forum, community building, information repository, organizer of direct support for certain scientific research.
fund & support the study of factors that either predict mortality & morbidity or influence improvements in longevity, health, and wellness
Community building fellowship program for people to build, join, or invest in longevity biotech projects.
Address the most challenging obstacles genuinely effective treatments to prevent & reverse human age-related disease. Flagship research program is combination therapies in mice.
Connects longevity researchers, investors, and entrepreneurs to create community and collaboration. Hosts networking events and conferences.
TBD....
Funding research and development of medical technologies to extend the healthy human lifespan, accessible to everyone.
Fundamental and translational geroscience spanning the hallmarks of aging, senescence, genome instability, metabolism, inflammation, and age-related disease.
Fundamental molecular, physiological, and evolutionary mechanisms of aging, including mitochondrial proteostasis, genome stability, metabolism, and neurobiology.
independent biomedical R&D and education institution focused on regenerative & aging biology and medicine
Making 90 the new 50 by 2030. Incubate and sponsor mission-relevant ventures, fund research, and support projects and prizes to accelerate breakthroughs in longevity.
Primary mitochondrial disease research addressing disease mechanisms, diagnosis, clinical care, prevention, treatments, and cures.
Primary and secondary mitochondrial disease across children and adults, including clinical care, daily functioning, patient experience, and therapeutic-development readiness.
Mitochondrial disease research, patient support, education, awareness, and improved care across Canada.
Health and healthy longevity of companion animals, horses, and wildlife through research on cancer, chronic disease, infectious disease, genetics, environmental exposures, and other causes of morbidity and mortality.
Mitochondrial biology in health, aging, and disease, including mitochondrial genetics, oxidative phosphorylation, dynamics, mitophagy, metabolism, reactive oxygen species, and neurodegeneration.
Mucopolysaccharidoses and mucolipidoses, lysosomal storage disorders that affect the nervous system, skeleton, connective tissue, cardiopulmonary function, and other organs.
Several different projects including Impetus Grants for aging.
Geroscience, biological-aging measurement, aging clocks, and interventions intended to delay biological aging and extend healthspan in Asian populations.
Several different projects to fight aging.
Osteogenesis imperfecta and related collagen and bone-matrix disorders, including skeletal fragility, connective-tissue biology, musculoskeletal function, and clinical management.
"think-tank organization that operates with the mission of supporting and enabling effective and sustainable growth in the field of aging and longevity sciences"
Hutchinson-Gilford progeria syndrome, progeroid laminopathies, and their links to aging-related disorders, with emphasis on treatments and a cure.
Research cooperative & independent research laboratory working towards regenerative therapies for aging, using synthetic biology, systems biology, & AI.
Cockayne syndrome, a transcription-coupled DNA-repair disorder caused principally by ERCC8/CSA or ERCC6/CSB variants and associated with childhood neurodegeneration and segmental premature-aging features.
TBD (website calls itself a biotech startup but Alexander says publicly in talks that it's a nonprofit (eg Foresight Institute presentation 2023, Dublin Longevity Summit 2024)
Basic biology of aging, translational geroscience, age-related disease, interventions, and healthy longevity.
Systemic sclerosis and localized scleroderma, including autoimmune inflammation, excess collagen deposition, fibrosis, extracellular-matrix remodeling, vasculopathy, and organ injury.
aging information resource with educational pages and many databases (all also linked from the databases table on this website)
Develop & promote therapies that cure/prevent aging diseases & disabilities by repairing damage that builds up w/ aging.
| Select up to four records | ||||||
|---|---|---|---|---|---|---|
| 2060.Life | community of scientists, VCs, MDs, & entrepreneurs who believe in radical life extension w/ mission to defeat Aging by 2060, by R&D, advocacy, hubs, & growing ecosystem | — | — | — | — | |
| Academy for Health & Lifespan Research | — | 2019 | — | — | — | |
| Afrolongevity | Solve aging, preserve Africa’s biodiversity, make aging a treatable disease for a healthy lifespan | — | — | — | — | |
| Age Reversal Network | — | — | — | — | — | |
| Aging Biology Foundation | — | — | — | — | — | |
| Aging Intervention Foundation | — | — | — | — | — | |
| AgingBiotech.info (this website!) | Concise, structured info on the field as sortable/filterable tables: Books, blogs, companies, conferences, databases, diagnostics, journals, nonprofits, objections, podcasts, videos, etc. | 2019 | — | — | — | |
| AKC Canine Health Foundation | Canine health research, including a dedicated program on the biology of aging, older-dog health, cognitive dysfunction, and diseases and conditions associated with aging. | 1995 | Funds peer-reviewed research and training grants, shares research findings with veterinary and dog communities, and supports comparative and One Health studies across the canine lifespan. | Raleigh, North Carolina | Founded by the American Kennel Club but established as an independent nonprofit; its aging portfolio includes Dog Aging Project-linked work and canine cognitive-dysfunction research. | |
| Alliance for Aging Research | Accelerates the pace of scientific discoveries in aging by working to increase funding/focus for aging at NIH/FDA & with other efforts. | 1986 | — | — | — | |
| Alliance for Longevity Initiatives (A4LI) | The field's first 501c4, for social and political action to combat age-related chronic conditions. | 2021 | — | — | — | |
| Alliance for Longevity Science, Arts & Entertainment (ALSAE) | — | 2024 | — | — | — | |
| Alzheimer's Drug Discovery Foundation | Drug discovery, biomarkers, and prevention programs for Alzheimer's disease grounded in the biology of aging | 1998 | Venture philanthropy funding for high-risk translational research in academia and biotechnology companies | New York, New York | Supports novel aging-biology targets that are too early for conventional pharmaceutical or federal funding | |
| Amaranth (Foundation) | "Funding ambitious research in longevity and neuroscience" | — | — | — | — | |
| American Aging Association (AGE) | Dedicated to aging research | 1970 | — | — | — | |
| American Federation for Aging Research (AFAR) | Advance Healthy Aging through Biomedical Research with grants & fellowships, plus other initiatives. | 1981 | — | — | — | |
| Amyloidosis Foundation | Systemic amyloidosis, including protein misfolding, amyloid formation and deposition, proteostasis, biomarkers, organ damage, and therapeutic development. | 2007 | Provides annual grants for early-career basic biomedical and clinical researchers, travel grants, patient support, professional education, and amyloidosis awareness programs. | Clarkston, Michigan | Formed in 2007 by the merger of the Amyloidosis Research Foundation and Amyloidosis Support Network; its research program supports early-career investigators studying systemic amyloidosis. | |
| Ara Parseghian Medical Research Fund | Niemann-Pick disease type C, a lysosomal cholesterol-trafficking and storage disorder with progressive neurodegeneration. | 2016 | Runs a competitive international grant program, supports gene-therapy, newborn-screening, biomarker, clinical-endpoint and small-molecule initiatives, and convenes collaborative NPC research through Notre Dame. | Notre Dame, Indiana | The current Notre Dame fund was established in 2016 to carry forward the work and grantmaking of the independent Ara Parseghian Medical Research Foundation launched in 1994. | |
| Autophagy, Inflammation and Metabolism Center | Fundamental and translational autophagy research and its intersections with inflammation, metabolism, cell and tissue homeostasis, and disease. | — | A University of New Mexico Center of Biomedical Research Excellence that supports research projects, pilot awards, junior-investigator development, scientific exchange, and shared autophagy and metabolism core facilities. | Albuquerque, New Mexico | Based in the University of New Mexico School of Medicine's Department of Molecular Genetics and Microbiology and supported through NIH COBRE grant P20GM121176. | |
| Barth Syndrome Foundation | Barth syndrome, an inherited mitochondrial disorder involving cardiolipin remodeling, cardiomyopathy, skeletal-muscle weakness, neutropenia, growth delay, and metabolic dysfunction. | 2000 | Funds and facilitates basic, translational, and clinical research; connects families, clinicians, and scientists; maintains medical and educational resources; and supports participation in research. | Larchmont, New York | Worldwide patient and research organization dedicated specifically to Barth syndrome, with research grants spanning underlying biochemistry, genetics, disease models, natural history, and treatment development. | |
| Batten Disease Support, Research, and Advocacy Foundation | Batten disease and neuronal ceroid lipofuscinoses, inherited lysosomal storage disorders characterized by intracellular lipopigment accumulation and progressive neurodegeneration. | 1987 | Funds and facilitates research, coordinates a global research initiative, provides family support and education, builds scientific and patient networks, and advocates for treatments and policy change. | Gahanna, Ohio | Current name expands the former Batten Disease Support & Research Association identity to state its support, research, and advocacy roles explicitly. | |
| Betterhumans | Directly does stem cell & gene-editing experiments towards delaying aging & rejuvenating vital organs, ultimately radically extending human lifespan. | 2013 | — | — | — | |
| Biogerontology Research Foundation | Develop UK longevity industry, academia, & policy, and help scale global longevity industry. | 2008 | — | — | — | |
| Bloom Syndrome Association | Bloom syndrome, a BLM helicase and DNA-repair disorder marked by genomic instability, growth restriction, immune problems, and elevated cancer risk. | — | Maintains an international patient community and registry, develops patient-centered research priorities, convenes a research council, provides education and support, and funds seed research. | — | Its SECURE research strategy prioritizes safer care, effective treatments, natural-history evidence, a global registry, gene-therapy and genome-editing research, and patient partnership. | |
| BrightFocus Foundation | Research on Alzheimer's disease and related dementias, age-related macular degeneration, and glaucoma, spanning disease mechanisms, diagnostics, prevention, and treatments. | 1973 | Awards peer-reviewed grants worldwide for early-stage basic, translational, and clinically oriented research through three specialized programs and trains early-career brain and vision scientists. | Clarksburg, Maryland | Operates the Alzheimer's Disease Research, Macular Degeneration Research, and National Glaucoma Research grant programs. | |
| British Longevity Society | — | 1992 | — | — | — | |
| British Society for Research on Aging (BSRA) | Promoting & funding research into the causes & effects of the aging process. | 1939 | — | — | — | |
| Buck Institute for Research on Aging | First independent biomedical research institute focused solely on aging. Mission is to end the threat of age-related disease for this and future generations. | 1999 | — | — | — | |
| California Institute for Regenerative Medicine | Regenerative medicine, stem-cell research, and cell and gene therapy development for diseases with unmet medical needs. | 2004 | A public grant-making agency that supports discovery, preclinical, and clinical research, shared infrastructure, workforce training, manufacturing, and patient-access programs; it does not conduct the funded research itself. | California | Created by California voters through Proposition 71; it is a taxpayer-funded public agency rather than an independent nonprofit charity. | |
| Canadian Longevity Association | — | — | — | — | — | |
| CECAD Cluster of Excellence | Molecular and cellular mechanisms of aging and aging-associated metabolic, cardiovascular, renal, cancer, neurodegenerative, and other diseases. | 2007 | Multidisciplinary basic and translational research integrating cellular stress, organelle quality, genome stability, metabolism, inflammation, inter-tissue signaling, and environmental effects. | Cologne | University of Cologne cluster supported by the German Excellence Initiative with university-hospital, Max Planck, and DZNE partners. | |
| Cell Stress Society International | Cellular and environmental stress responses, molecular chaperones, heat-shock proteins, protein folding, and proteostasis in health and disease. | 1999 | Advances basic, translational, and interdisciplinary research through international symposia, its journal Cell Stress & Chaperones, scientific collaboration, mentoring, awards, and trainee support. | — | A membership society focused on stress and chaperone biology; its proteostasis relevance includes Hsp90, Hsp70, co-chaperones, protein-folding stress, and chaperone-based therapeutic research. | |
| Clock Foundation (Epigenetic Clock Development Foundation) | Making epigenetic aging clocks more accessible for use with preclinical & clinical studies, including clocks that predict future healthspan/lifespan & clocks for diverse mammalian species. | — | — | — | — | |
| Club Francophone de l'Autophagie | Autophagy research, including autophagy mechanisms, physiology, aging, neurodegeneration, infection, immunity, metabolism, and disease. | 2011 | Connects French-speaking autophagy laboratories, organizes scientific meetings, maintains research and methods resources, supports trainee participation, and awards travel grants and a thesis prize. | France and the French-speaking research community | A member association and research network rather than a university institute or independent grant-making foundation. | |
| Coalition for Radical Life Extenstion | Education, resources, community, public policy advoacy towards curing aging / unlimited lifespans. | — | — | — | — | |
| Cure Alzheimer’s Fund | Alzheimer's disease mechanisms and interventions, including age-related proteostasis decline, amyloid and tau biology, protein clearance, inflammation, genetics, and resilience. | — | Funds investigator-led foundational, translational, drug-discovery, and clinical research guided by external scientific leadership and collaborative consortia. | — | — | |
| Cure Mito Foundation | Leigh syndrome and mitochondrial disease research, with an initial emphasis on SURF1-related Leigh syndrome. | 2018 | Funds patient-centered research, convenes an annual Leigh syndrome symposium, and maintains a global patient registry and research resources for the mitochondrial-disease community. | — | Established as Cure SURF1 Foundation in 2018 and renamed Cure Mito Foundation in 2021 as its scope expanded beyond SURF1. | |
| Cure Parkinson’s | Disease-modifying Parkinson's research, including cellular waste disposal, protein aggregation, oxidative stress, mitochondrial function, and regenerative approaches. | 2005 | Funds international preclinical and clinical disease-modification projects through a quarterly grant program and advances prioritized candidates through its international Linked Clinical Trials initiative. | London | Cure Parkinson’s is the operating name of The Cure Parkinson’s Trust; its grants focus on interventions intended to slow, stop, or reverse Parkinson’s rather than symptomatic relief alone. | |
| Cure Sanfilippo Foundation | Research and therapeutic development for Sanfilippo syndrome, a lysosomal storage disorder also known as mucopolysaccharidosis type III. | — | Funds and builds research collaborations across gene therapy, enzyme replacement, substrate reduction, stem-cell approaches, and other experimental avenues while supporting affected families. | Columbia, South Carolina | Family-led charity supporting multiple investigational approaches to restoring lysosomal function and treating Sanfilippo syndrome. | |
| Cure VCP Disease | VCP-associated multisystem proteinopathy affecting muscle, bone, brain, and peripheral nerves, with relevance to protein degradation, autophagy, endoplasmic-reticulum quality control, lysosomal function, and mitochondrial homeostasis. | 2018 | Funds research, maintains a patient registry and research network, supports natural-history and biospecimen studies, convenes scientific meetings, and provides standardized preclinical assays and disease models for therapy development. | Warner Robins, Georgia | Its preclinical toolbox includes autophagy-flux, protein-unfolding, motor-neuron-survival, patient-derived cell, organoid, and animal-model resources for VCP research. | |
| CurePSP | Progressive supranuclear palsy, corticobasal degeneration, and multiple system atrophy research, including tau biology, autophagy, proteostasis, lysosomal biology, epigenetics, biomarkers, and regenerative approaches. | 1990 | Funds New Investigator and Enterprise research grants, student fellowships, biomarker development, genetics research, scientific meetings, and an international clinical Center of Care network. | New York, New York | Its research grant priorities explicitly include autophagy and proteostasis, tau strains, lysosomal biology, epigenetics, cell replacement, biomarkers, and proof-of-concept clinical trials. | |
| Dog Aging Institute and it's Dog Aging Project | Study tens of thousands of companion dogs for 10 years for maximizing healthy longevity. | — | — | — | — | |
| European Research Institute for the Biology of Ageing | Fundamental mechanisms of cellular and tissue aging, including protein aggregation and proteostasis, stem-cell aging, senescence, DNA replication and repair, genome stability, gene regulation, and metabolism. | 2013 | Multidisciplinary laboratory research using model systems and technology platforms to understand why cells and tissues lose function with age and to identify strategies against age-related disease. | Groningen | A research unit within UMCG and the University of Groningen ecosystem rather than an independent charity. | |
| EveryCat Health Foundation | Feline health research, including mitochondrial and antioxidant biomarkers of aging, cognitive dysfunction, geriatric care, and age-related disease. | 1968 | Peer-reviewed research grants, new-investigator awards, disease-specific funds, research summaries, education, and global support for academic, veterinary-practice, and industry investigators. | Wyckoff, New Jersey | Founded as Winn Feline Foundation and renamed EveryCat Health Foundation in 2021; current aging grants include blood mitochondrial and antioxidant biomarkers and feline cognitive dysfunction. | |
| Fanconi Cancer Foundation | Fanconi anemia, cancers driven by defects in the FA/BRCA DNA-repair pathway, bone-marrow failure, and systemic inflammatory and aging manifestations. | — | Funds peer-reviewed basic, translational, preclinical, and clinical research on pathogenesis, gene therapy and editing, biomarkers, cancer prevention and detection, and shared research resources. | — | — | |
| Forever Healthy Foundation | Efforts to vastly extend healthy lifespan via several initiatives including reseacrh funding, supporting startups, events, research summaries. | 2013 | — | — | — | |
| Friedreich's Ataxia Research Alliance | Friedreich's ataxia, a frataxin-deficiency disorder involving mitochondrial iron-sulfur-cluster biology, oxidative stress, neurodegeneration, cardiomyopathy, skeletal-muscle impairment, and diabetes. | — | Funds competitive basic, translational and clinical grants; develops shared models, biorepositories, biomarkers and endpoints; coordinates global clinical infrastructure; convenes scientific forums; and supports investigator training. | — | Current grant mechanisms span general research, cardiac disease, translational work, research collaboration, clinician-scientist development, postdoctoral and graduate awards, and targeted biomarker requests. | |
| Gerontological Society of America | Interdisciplinary aging research, education, clinical practice, policy, and dissemination | 1945 | Connects researchers and practitioners, publishes peer-reviewed journals, and convenes an Annual Scientific Meeting | Washington, DC | Includes biological scientists alongside medical, behavioral, social, and policy researchers | |
| Glenn Foundation for Medical Research | extend healthy years via research on mechanisms of normal human aging & physiological decline, to translate research into interventions that will extend healthspan with lifespan | — | — | — | — | |
| Global Healthspan Policy Institute (GHPI) | Public policy think tank for R&D towards treatments for underlying causes of aging-related disease. Education, policy research, lobbying, & coalition development. | 2015 | — | — | — | |
| Grey Muzzle | Welfare, medical access, adoption, shelter diversion, and long-term home retention for senior dogs, with national data collection on older-dog needs and outcomes. | 2008 | Makes grants to animal-welfare nonprofits, collects program data, tests and shares senior-dog service models, and supports veterinary care, adoption readiness, foster care, hospice, and owner-retention programs. | Raleigh, North Carolina | A grantmaker supporting senior-dog welfare programs, with applied service evidence and outcomes for at-risk older dogs. | |
| Harvard Stem Cell Institute | Stem-cell biology and regenerative medicine, including how aging and fibrosis affect disease, tissue repair, and therapeutic development. | 2004 | Coordinates research faculty and laboratories across Harvard schools, centers, teaching hospitals, and partner organizations; supports shared research resources, collaborations, disease programs, and translation toward the clinic. | Boston, Massachusetts | A university-wide research network rather than a separate independent charity; donations are made to the President and Fellows of Harvard College for HSCI. | |
| Heales (Healthy Life Extension Society) | — | 2009 | — | — | — | |
| Health Extension Foundation | — | 2012 | — | — | — | |
| Health Longevity Medicine Society (HLMS) | TBD.... | — | — | — | — | |
| Healthspan Action Coalition | Public policy coalition on healthspan. | 2022 | — | — | — | |
| Healthy Aging & Longevity Research Institute (HALO) | — | — | — | — | — | |
| Hevolution Foundation | Grants & early sage investment to grow the number of researchers, companies, & amount of funding in the aging/longevity field. | 2021 | — | — | — | |
| Huntington’s Disease Foundation | Huntington's disease mechanisms and therapeutics, including somatic CAG-repeat instability, protein aggregation, neuronal vulnerability, gene regulation, and related neurodegeneration. | — | Funds research grants, postdoctoral fellowships, career-advancement awards, and large collaborative Transformative Research Awards, guided by an international scientific advisory board. | New York, New York | Formerly the Hereditary Disease Foundation; its current funding programs include work on disease mechanisms, therapeutics, and somatic repeat instability in Huntington's disease. | |
| Institute for Systems Biology | Systems biology and translational biomedical research, including multimodal studies of human longevity and age-related disease | 2000 | Integrates genetic, proteomic, metabolomic, clinical, and population data to identify pathways associated with healthy and exceptional longevity | Seattle, Washington | Contributes systems-biology analysis to the NIA-funded Longevity Consortium | |
| Institute of Molecular Biology | Molecular mechanisms of aging, development, and disease, with emphasis on gene regulation, epigenetics, DNA repair, genome stability, telomere biology, and proteostasis. | 2011 | Independent basic research groups combine molecular, cellular, biophysical, and computational approaches with shared genomics, proteomics, microscopy, and other core facilities. | Mainz | Research themes include genome stability, telomere biology, DNA repair, epigenetics, chromatin, proteostasis, protein quality control, and phase separation in aging and age-related disease. | |
| International Institute of Longevity | — | 2018 | — | — | — | |
| International Longevity Alliance (ILA) | — | 2013 | — | — | — | |
| International Registry of Werner Syndrome | Werner syndrome and atypical segmental progeroid syndromes involving WRN helicase, genome maintenance, premature age-related disease, cancer, atherosclerosis, diabetes, osteoporosis, and cataracts. | — | Provides molecular diagnosis, collects clinical and pedigree data, banks DNA and cryopreserved cells, identifies WRN and other progeroid-syndrome variants, and shares de-identified materials with qualified researchers. | Seattle, Washington | An academic registry and biospecimen repository housed in the University of Washington Department of Laboratory Medicine and Pathology, rather than an independent nonprofit corporation. | |
| ISOAD (International Society on Aging & Disease) | — | 2015 | — | — | — | |
| Kitalys Institute | — | 2020 | — | — | — | |
| Leibniz Institute on Aging – Fritz Lipmann Institute | Biology of aging at molecular, cellular, organismal, and systems levels, with emphasis on root causes and prevention of age-associated disease. | — | Fundamental research across diverse species and model systems, integrating omics, the exposome, microbiome, immune aging, evolutionary biology, and technology transfer. | Jena | Federally and state-funded member institute of the Leibniz Association. | |
| Lifespan.io aka Life Extension Advocacy Foundation (LEAF) | Aging research news, crowdfunding, and advocacy. Social media outreach, community building, & education. | 2014 | — | — | — | |
| Loeys-Dietz Syndrome Foundation | Loeys-Dietz syndrome and related genetic aortic and connective-tissue disease involving TGF-beta signaling, extracellular-matrix integrity, arterial aneurysm, and multisystem manifestations. | — | Supports clinical and basic research, research recruitment, medical education, diagnostic awareness, family resources, and community programs within The Marfan Foundation. | — | — | |
| LongeCity | Open discussion forum, community building, information repository, organizer of direct support for certain scientific research. | — | — | — | — | |
| Longer Life Foundation | fund & support the study of factors that either predict mortality & morbidity or influence improvements in longevity, health, and wellness | 1998 | — | — | — | |
| Longevity Biotech Fellowship | Community building fellowship program for people to build, join, or invest in longevity biotech projects. | 2022 | — | — | — | |
| Longevity Biotechnology Association | — | 2021 | — | — | — | |
| Longevity Escape Velocity Foundation (LEVF) | Address the most challenging obstacles genuinely effective treatments to prevent & reverse human age-related disease. Flagship research program is combination therapies in mice. | 2022 | — | — | — | |
| Longevity Global (GL) | Connects longevity researchers, investors, and entrepreneurs to create community and collaboration. Hosts networking events and conferences. | 2022 | — | — | — | |
| Longevity San Juan | TBD.... | — | — | — | — | |
| Longevity Science Foundation | Funding research and development of medical technologies to extend the healthy human lifespan, accessible to everyone. | 2021 | — | — | — | |
| Masonic Institute on the Biology of Aging and Metabolism | Fundamental and translational geroscience spanning the hallmarks of aging, senescence, genome instability, metabolism, inflammation, and age-related disease. | — | University research teams use cellular and mouse models, specialized genome-instability resources, drug development, and human clinical studies to test interventions intended to extend healthspan. | — | University of Minnesota Medical School institute studying how the hallmarks of aging can be manipulated, including senolytic interventions and DNA-repair-deficient models. | |
| Max Planck Institute for Biology of Ageing | Fundamental molecular, physiological, and evolutionary mechanisms of aging, including mitochondrial proteostasis, genome stability, metabolism, and neurobiology. | — | Interdisciplinary basic research using model organisms, patient samples, long-lived families, core facilities, and collaborations that bridge laboratory and clinical research. | Cologne | Part of the independent nonprofit Max Planck Society and the Cologne aging-research network with CECAD and university-hospital partners. | |
| MDI Biological Laboratory | independent biomedical R&D and education institution focused on regenerative & aging biology and medicine | 1898 | — | — | — | |
| Methuselah Foundation | Making 90 the new 50 by 2030. Incubate and sponsor mission-relevant ventures, fund research, and support projects and prizes to accelerate breakthroughs in longevity. | 2001 | — | — | — | |
| Mito Foundation | Primary mitochondrial disease research addressing disease mechanisms, diagnosis, clinical care, prevention, treatments, and cures. | — | Funds discovery, clinical, health-services, and public-health research through investigator grants, fellowships, incubator awards, and strategic partnerships. | — | — | |
| MitoAction | Primary and secondary mitochondrial disease across children and adults, including clinical care, daily functioning, patient experience, and therapeutic-development readiness. | 2005 | Free patient and caregiver support, expert education, outreach, advocacy, clinical-research initiatives, community aggregation, and engagement with academic and industry therapeutic developers. | — | Began as the Mitochondrial Disease Action Committee and adopted the MitoAction name in 2008; its remit centers on quality of life and practical support alongside clinical-research engagement. | |
| MitoCanada Foundation | Mitochondrial disease research, patient support, education, awareness, and improved care across Canada. | — | Supports patient-focused research, research participation and registries, education, advocacy, and connections among patients, families, clinicians, and scientists. | Oakville, Ontario | An independent national health foundation rather than a hospital or university research unit. | |
| Morris Animal Foundation | Health and healthy longevity of companion animals, horses, and wildlife through research on cancer, chronic disease, infectious disease, genetics, environmental exposures, and other causes of morbidity and mortality. | 1948 | Funds peer-reviewed animal-health studies worldwide and directly operates the longitudinal Golden Retriever Lifetime Study with recurring owner, veterinary, and biospecimen data collection. | Denver, Colorado | Its Golden Retriever Lifetime Study follows a large canine cohort and makes longitudinal data and biospecimens available for research on cancer, disease risk, biomarkers, and the life course of aging in dogs. | |
| MRC Mitochondrial Biology Unit | Mitochondrial biology in health, aging, and disease, including mitochondrial genetics, oxidative phosphorylation, dynamics, mitophagy, metabolism, reactive oxygen species, and neurodegeneration. | 2009 | Multidisciplinary basic and translational research that connects biochemical mechanisms, cellular and organismal models, human mitochondrial disease, therapeutic development, and clinical collaboration. | Cambridge | A University of Cambridge department whose present MRC Mitochondrial Biology Unit identity dates from 2009; its groups include mitochondrial genome engineering and PINK1/Parkin mitophagy research. | |
| National MPS Society | Mucopolysaccharidoses and mucolipidoses, lysosomal storage disorders that affect the nervous system, skeleton, connective tissue, cardiopulmonary function, and other organs. | — | Competitive research grants, scientific collaboration, clinical-trial information, family assistance, education, national conferences, awareness, and policy advocacy. | Durham, North Carolina | Its research program supports multiple grant tiers, early-career investigators, translational work, analysis of biospecimens and data, and clinical consensus projects across MPS and mucolipidosis. | |
| Norn Group | Several different projects including Impetus Grants for aging. | 2021 | — | — | — | |
| NUHS Centre for Healthy Longevity | Geroscience, biological-aging measurement, aging clocks, and interventions intended to delay biological aging and extend healthspan in Asian populations. | 2022 | Integrated preclinical and clinical research using age-appropriate models, biomarker and AI platforms, and human studies of candidate geroprotectors. | Singapore | Clinical and translational partner of the National University of Singapore Healthy Longevity Translational Research Programme. | |
| Open Longevity | Several different projects to fight aging. | 2016 | — | — | — | |
| Osteogenesis Imperfecta Foundation | Osteogenesis imperfecta and related collagen and bone-matrix disorders, including skeletal fragility, connective-tissue biology, musculoskeletal function, and clinical management. | 1970 | Funds postdoctoral research fellowships and other OI studies, maintains a patient registry and clinic directory, shares research opportunities, convenes professional and family meetings, and provides education and support. | Gaithersburg, Maryland | Its Michael Geisman Fellowship Grant supports postdoctoral investigators working on OI-relevant projects and building expertise in OI research. | |
| Phaedon Institute | "think-tank organization that operates with the mission of supporting and enabling effective and sustainable growth in the field of aging and longevity sciences" | 2022 | — | — | — | |
| Progeria Research Foundation | Hutchinson-Gilford progeria syndrome, progeroid laminopathies, and their links to aging-related disorders, with emphasis on treatments and a cure. | — | Builds research infrastructure through a medical and research database, cell and tissue bank, diagnostic program, scientific workshops, grants, and clinical trials; advances gene-, RNA-, cell-, and small-molecule therapies. | — | — | |
| Regenerative Sciences Institute | Research cooperative & independent research laboratory working towards regenerative therapies for aging, using synthetic biology, systems biology, & AI. | 1994 | — | — | — | |
| Riaan Research Initiative | Cockayne syndrome, a transcription-coupled DNA-repair disorder caused principally by ERCC8/CSA or ERCC6/CSB variants and associated with childhood neurodegeneration and segmental premature-aging features. | 2021 | Funds and coordinates translational research, including CSA gene-replacement development, drug-repurposing screens, patient registry infrastructure, preclinical studies, manufacturing, and regulatory work. | New York, New York | The organization funded the CSA/ERCC8 AAV9 program from preclinical work through manufacturing and regulatory review; its June 2026 report records a first individual administration without establishing wider clinical efficacy. | |
| RLE Group | TBD (website calls itself a biotech startup but Alexander says publicly in talks that it's a nonprofit (eg Foresight Institute presentation 2023, Dublin Longevity Summit 2024) | — | — | — | — | |
| Robert & Arlene Kogod Center on Aging | — | — | — | — | — | |
| Sam and Ann Barshop Institute for Longevity and Aging Studies | Basic biology of aging, translational geroscience, age-related disease, interventions, and healthy longevity. | 2001 | Basic, clinical, and population research supported by NIH aging centers, the Interventions Testing Program, training programs, and an on-site clinical research unit. | San Antonio, Texas | UT San Antonio institute hosting NIA-supported Nathan Shock, Claude D. Pepper, population-aging, and Interventions Testing Program activities. | |
| Scleroderma Research Foundation | Systemic sclerosis and localized scleroderma, including autoimmune inflammation, excess collagen deposition, fibrosis, extracellular-matrix remodeling, vasculopathy, and organ injury. | 1987 | Funds peer-reviewed basic, translational and clinical research; recruits investigators from fibrosis, immunology and genetics; supports longitudinal registries; and runs collaborative platform-trial and scientific-workshop programs. | — | Its research portfolio includes the CONQUER longitudinal registry, GRASP study of disease biology in African American patients, and the CONQUEST Phase 2 platform trial in systemic-sclerosis-associated interstitial lung disease. | |
| Senescence.info | aging information resource with educational pages and many databases (all also linked from the databases table on this website) | — | — | — | — | |
| SENS Research Foundation (SRF aka SENS) | Develop & promote therapies that cure/prevent aging diseases & disabilities by repairing damage that builds up w/ aging. | 2009 | — | — | — |